I came across this small study researching AMH levels in women undergoing surgery for endometriosis. The study followed postoperative pregnancy rates between women with low and normal AMH levels. There was no difference in pregnancy rates between the two groups.
I think it’s so important to understand that AMH might impact the amount of eggs you make in an IUI/IVF cycle, but it doesn’t indicate your chances for a successful pregnancy.
A quick analyses of the study:
• A new study (so many are outdated) and focuses on pregnancy rates between the two groups.
• Women with low AMH and severe endometriosis have a good success conceiving naturally after surgery. This is great news, as endometriosis will inhibit a women’s chance of conceiving – never mind the added stressor of AHM. There’s even evidence surgery for women in their 20’s and 30’s have good fertility outcomes.
• This study is a small group study and comprises of women in their 30’s.
• There’s no mention if IUI/IVF was utilized to conceive.
If you are dealing with low AMH, acupuncture and Chinese herbs can help to improve your egg quality and prepare your body for IVF.
Does preoperative antimüllerian hormone level influence postoperative pregnancy rate in women undergoing surgery for severe endometriosis?
Emanuela Stochino-Loi, M.D.,Basma Darwish, M.D.,Oana Mircea, M.D.,Salma Touleimat, M.D.,Jenny-Claude Millochau, M.D.,Carole Abo, M.D.,Stefano Angioni, M.D., Ph.D., Horace Roman, M.D., Ph.D.
Among 180 women enrolled in the study, 134 (74.4%) were assigned to group A and 46 (25.6%) to group B. The women’s ages were, respectively, 30 ± 3.8 and 32 ± 4.6 years. Pregnancy was achieved by 134 (74.4%) patients, and conception was spontaneous in 74 of them (55.2%). Pregnancy rates in groups A and B were, respectively, 74.6% (100 women) and 73.9% (34 women), while spontaneous conception represented 54% (54 women) and 58.8% (20 women). The probability of pregnancy at 12, 24, and 36 months after surgery in groups A and B was comparable, respectively, 65% (95% confidence interval [CI], 55%–75%), 77% (95% CI, 86%–68%), and 83% (95% CI, 90%–75%) versus 50% (95% CI, 69%–34%), 77% (95% CI, 90%–61%), and 83% (95% CI, 94%–68%). Supplementary analysis in women with normal (≥2 ng/mL), low (1–1.99 ng/mL), and very low (<1 ng/mL) AMH level showed an inverse relationship between AMH level, age, and antecedents of miscarriage; however, postoperative pregnancy rates were comparable among the three groups at 12 and 24 months, respectively, 59.5% (95% CI, 49.3%–70%) and 77.4% (95% CI, 68%–85.4%); 57.1% (95% CI, 34%–83%) and 78.6% (95% CI, 55.2%–94.8%); and 46.7% (95% CI, 25.6%–73.7%) and 73.3% (95% CI, 50.4%–91.7%).
The probability of postoperative pregnancy was comparable between women with low and normal AMH level who were managed for stage 3 and 4 endometriosis and who were a mean age of 30 years. However, the small sample size might have been unable to detect differences in pregnancy and live-birth rates between the two groups. As the majority of pregnancies were spontaneous, our results suggest that surgical management may be offered to young patients with severe endometriosis and reduced ovarian reserve with good fertility outcomes.